The safe & effective leucocyte-reduced platelet rich plasma
The application of Platelet-Rich Plasma (PRP) in soft tissue defects, is a specialist area within regenerative medicine.
PRP refers to plasma, i.e., the liquid portion of the blood in which platelets are concentrated.
PRP is prepared from the patient’s own blood
Regen PRP: the patient’s platelet concentrate prepared with RegenKit® products.
In addition to their role in haemostasis, platelets are key factors in tissue repair mechanisms.1 They provide essential growth factors, such as FGF, PDGF, TGF-β, EGF, VEGF, IGF, which are involved in stem cell migration, differentiation, and proliferation. Platelet growth factors also stimulate fibroblasts and endothelial cells to induce the deposition of new extracellular matrix and neo-vascularisation, respectively.
Plasma contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes, growth factors (such as IGF and HGF), and proteins. Among the plasma proteins, the molecules involved in the coagulation process allow the formation of the fibrin polymer that serves as a scaffold for cell migration and new tissue generation.2
- Best minimally invasive treatment option
- Favours healing process
- Provides the needed growth factors
- Safety insured by the use of a closed system
- Standardised PRP isolation whatever the patient or the operator
- Effectiveness of PRP isolation insured by the use of an automated system
Regen PRP: the patient’s platelet concentrate prepared with RegenKit® products.
In addition to their role in haemostasis, platelets are key factors in tissue repair mechanisms.1 They provide essential growth factors, such as FGF, PDGF, TGF-β, EGF, VEGF, IGF, which are involved in stem cell migration, differentiation, and proliferation. Platelet growth factors also stimulate fibroblasts and endothelial cells to induce the deposition of new extracellular matrix and neo-vascularisation, respectively.
Plasma contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes, growth factors (such as IGF and HGF), and proteins. Among the plasma proteins, the molecules involved in the coagulation process allow the formation of the fibrin polymer that serves as a scaffold for cell migration and new tissue generation.2
- Best minimally invasive treatment option
- Favours healing process
- Provides the needed growth factors
- Safety insured by the use of a closed system
- Standardised PRP isolation whatever the patient or the operator
- Effectiveness of PRP isolation insured by the use of an automated system
RegenPRP™ is a well accepted treatment and proven in many clinical studies.
Technological benefits
- Standardized preparation
- Minimum Blood Requirements
- Closed-Loop System: maximized safety
- Stable Physical Separation
- Reversible, Pharmaceutical-Grade Anticoagulation
- pH Neutral Anticoagulant for Patient Tolerability
- Rapid Centrifugation: 5 minutes
- Ease of Preparation: efficient & reproducible
- Facilitates and streamlines routine practice
Biological benefits
- Standardized, Leukocyte-Poor, and Consistent
- Platelet Recovery >80%
- High Platelet Quality: viability & functionality
- Full Plasma Recovery: maximized Growth factor and fibrinogen content
- Maximized Purity: >99.7% RBC depletion
- Extreme Cellular Selectivity: ~96.5% GRN & 70-80% MNC elimination
Scientific benefits
- Demonstrated safety and efficacy
- Evidence-based outcomes for numerous therapeutic indications
- Large number of clinical studies, with over 200 publications